Myktybayeva Raya Zhausygulkyzy's research addresses current issues in biology and veterinary science, specifically obtaining microbial physiologically active substances (proteins, amino acids, vitamins, antibacterial agents, etc.), as well as "Development of domestic probiotic preparation based on associated strains of lactic acid bacteria to enhance the immune system of farm offspring" on an industrial scale and their use in animal husbandry, which is a valuable contribution to solving the problem of the food program of the Republic of Kazakhstan. The main contractor for the implementation of 5 research projects of the Ministry of Education and Science of the Republic of Kazakhstan from 2017 to 2025 is the head of scientific projects from 2023 to 2025. More than 300 scientific and methodological works, including 1 textbook, 4 textbooks marked by the Ministry of Education and Science of the Republic of Kazakhstan, 1 foreign. Author of 44 patents and other protective documents. His published scientific works have great scientific and practical value. Under his supervision, 12 master's theses were defended.
1. In 1982, Almaty Zootechnical Veterinary Institute Veterinarian
2. Candidate of Veterinary Sciences
AP19677719 "Development of a domestic probiotic preparation based on associated strains of lactic acid bacteria to enhance the immune system of farm animals."
Grant funding from the Ministry of Science and Higher Education of the Republic of Kazakhstan.
Implementation period: 2023-2025.
Project Manager: Myktybayeva Raya Zhaksygulovna
Project executor:
Sansyzbay Ablai Rysbayuly
Alpeisov Shokhan Ashenovich
Kozhakhmetova Zubaira Amirbekovna
Boranbayeva Togzhan Kenzhetayevna
Musaev Asylbek Mailybaevich
Utebayev Zhasulan Maratovich
Zharylkasyn Ayaulym Ormankyzy
Orazalieva Madina Bazarbaevna
ARTICLES IN SCOPUS / WEB OF SCIENCE JOURNALS
- Myktybayeva, R., Özkaya, S., Şanlı, E. R., Yaşar, H., Tüzün, C. G., Koşkan, Boranbayeva, T., Otebayev, Z. & Alpeisov, S.«Determination of the Probiotic Potential and Metabolic Function of Lactobacillus Strains for Healthy Calf Rearing» OnLine Journal of Biological SciencesVolume 25 No. 3, 2025, 607-616DOI: https://doi.org/10.3844/ojbsci.2025.607.616 Автор корреспонденции: Мыктыбаева Р.Ж.
- Özkaya, S., Işık, A. R., Boranbayeva, T., Karahan, A. G., Tulemissova, Z., Myktybayeva, R., Sansyzbai, A., & Şanlı, E. R. (2025). Effect of Lactobacterin-TK2 and multispecies probiotics on calf health during suckling. Journal of the Hellenic Veterinary Medical Society, 76(4), 9877–9890.
- Nadtochii, L., Orazov, A., Ryskaliyeva, B., & Myktybayeva, R. Assessment of the Amino Acid Composition of Shubat from Western Kazakhstan. Applied Food Biotechnology, 12(1), 1-9.
- R. Myktybayeva, Z. Kozahmetova, A. Sansyzbay, T. Boranbayeva, A. Mussoyev, Zh. Otebayev and Ye. Impact of Factors on the Growth and Activity of Lactic Acid Bacteria for Controlling Pathogenic Microorganisms in Kazakhstan Dutbayev International Journal of Agriculture and Biosciences 2024 13(4): 617-625. DOI: https://doi.org/10.47278/journal.ijab/2024.165 (Scopus, Q2)
- Аlpeisov Shokhan, Myktybayeva Raya, Kozhakhmetova Zubaira, Boranbayeva Togzhan and Otebayev Zhassulan Increasing Resistance and Productivity of Broiler Chickens through Probiotics OnLine Journal of Biological Sciences, 25(1), 65-72. DOI: https://doi.org/10.3844/ojbsci. 2025.65.72 (Scopus, Q2)
- Tulemissova, Z. K., Ibazhanova, A. S., Myktybayeva, R. Z., Khussainov, D. M.,Mussoyev, A. M.,Kenzhebekova, Zh. Zh.,Torehanov, M. A. Bovine Interdigital Necrobacillosis Epizootic Data from Livestock Farms in Almaty Region of Kazakhstan between 2017 and 2019. Advances in Animal and Veterinary Sciences Открытый доступ Том 9, Выпуск 5, Страницы 761 – 765, 2021, DOI:
10.17582/journal.aavs/2021/9.5.761.765 (Scopus, Q3) - Boranbayeva, T.,Karahan, A. G.,Tulemissova, Zh.,Myktybayeva, R.,Özkaya, S. Properties of a New Probiotic Candidate and Lactobacterin-TK2 Against Diarrhea in Calves. Probiotics and Antimicrobial ProteinsТом 12, Выпуск 3, Страницы 918 - 9281 September, 2020, DOI:10.1007/s12602-020-09649-4 (Scopus, Q1)
- Tulemissova, Z. K.,Torehanov, M. A.,Myktybayeva, R. Zh., Ibazhanova, A. S.,Khussainov, D. M.,Batanova, Zh. M.,Usmangaliyeva, S. S. Comparison of Probiotic Lactobacillus acidophilus and Oxytetracycline for the Treatment of Early Stage Interdigital Necrobacillosis in Dairy Cows. World's Veterinary Journal Открытый доступ Том 10, Выпуск 3, Страницы 375 – 379 September 2020, DOI: 10.36380/scil. 2020.wvj 46 (Scopus, Q3)
ARTICLES IN JOURNALS RECOMMENDED BY THE COMMITTEE FOR QUALITY ASSURANCE IN SCIENCE AND HIGHER EDUCATION OF THE MINISTRY OF SCIENCE AND HIGHER EDUCATION OF THE REPUBLIC OF KAZAKHSTAN
1.R.Zh. Myktybaeva, Z.A. Kozhakhmetova, Sh.A. Alpeisov, A.R. Sansyzbai, S. Ozkaya. Antibiotic resistance of new strains of lactobacilli isolated from natural sources. Мicrobiology and virology ISSN 2304-585X№2 (45) 2024 С.262-274.
www. imv-journal.kz
https://doi.org/10.53729/MV-AS.2024.02.16
2.Kozhakhmetova Z.A., Myktybaeva R.Zh., Sansyzbai A.R., Lactose-fermenting ability of lactic acid bacteria isolated from natural sources. Science and Education No4-1 (77) 2024 p. 3-13.
DOI: https://doi.org/10.52578/2305-9397-2024-4-13-13
3.Boranbayeva T.K.,Озкайа С.,Sansizbay A.R.,Myktybayeva R.Zh.,Zhalelov D.B. Еfficacy of «emix» preparation and pathomorphological study of salmonellosis in calves. Наука и образование Science and education 1 - бөлім № 2-1 (75) 2024. С.204-211. DOI 10.52578/2305-9397-2024-2-1-204-211
4.Myktybaeva R.Zh., Tulemisova Zh.K., Kozhakhmetova Z.A., Ibraykan J.D.. The Influence of the Antagonistic Activity of Lactic Acid Bacteria Strains on the Causative Agent of Bovine Necrobacteriosis. Research, Results No. 1 (85) 2020. ISSN 2304-3334. Almaty - 2020. Pp. 132-137. https://izdenister.kaznaru.edu.kz/files/full/2020_1MONOGRAPHS AND TEXTBOOKS
1.Myktybaeva R.Zh., Veterinary Sanitary Microbiology Study Guide.- Almaty: Nur-Print LLP, 2021.-285 p.
2. Myktybaeva R.Zh., Microbiological Control of Animal Products: A Study Guide. - Almaty: Aitumar, 2024. - 137 p.
3.Мigtibayeva, Esimbetov, Seypullayev. Veterinarya mikrobiologiyasi ham immunologiyasi. Samargand mamleketlik veterinaria medicinasi, sharwashilig ham biotexnologialar universiteti Baspa-poligrafiya orayi, 2025.-172 b.
PATENTS
1.Patent of the Republic of Kazakhstan No37829. Immune system of offspring of agricultural animals and birds
Method for obtaining an associated probiotic preparation to increase activity / Myktybayeva R.Zh.., 20.02. 2026.
2. Patent of the Republic of Kazakhstan No111288. Lactobacillus helveticus - TRk 03 strain of lactic acid bacteria used for preparing probiotic preparations / Myktybayeva R.Zh.., 17.10.2025.
3.Patent of the Republic of Kazakhstan No. 8731. Method of serological diagnosis of cattle hypodermatosis
/ Myktybayeva R.Zh.., 22.12. 2023.
4. Patent of the Republic of Kazakhstan No 8732. Serological method of diagnosing dirofilaria in dogs. / Myktybayeva R.Zh.., 22.12. 2023.
5. Patent of the Republic of Kazakhstan No 8215. Complex insectoacaricide preparation for domestic and farm animals / Myktybayeva R.Zh.., 30.06. 2023.
6. Patent of the Republic of Kazakhstan No. 8323. Method of diagnosing bovine leukemia by enzyme immunoassay method / Myktybayeva R.Zh.., 04.08. 2023.
7. Patent of the Republic of Kazakhstan No. 8695. Method of serological diagnosis of horse rhinestrosis / Myktybayeva R.Zh.., 08.12. 2023.
8. Patent of the Republic of Kazakhstan No 8696. Patent of the Republic of Kazakhstan No 8695. Method of serological diagnosis of horse rhinestrosis / Myktybayeva R.Zh.., 08.12. 2023.
9. Patent of the Republic of Kazakhstan No 8697. Patent of the Republic of Kazakhstan No. Method for obtaining brucellosis-positive serum / Myktybayeva R.Zh.., 28.07. 2023.
OTHER PUBLICATIONS
Conference Proceedings
- 1. Myktybayeva, R., Sansyzbai, A., Kozhakhmetova, Z., Otebayev, Z., & Kyrgyzbay, N. (2025). The effect of the probiotic preparation “Lactobact-ARZ” on the dynamics of certain morphological and biochemical blood indicators in calves. In 2nd International Congress of Veterinary Medicinal Plants and Traditional Medicine: Proceeding book (pp. 123–127). Atatürk University – Urmia University. ISBN: 978-605-4934-51-5.
- Yernazarova Sandugash Tukenovna, Myktybayeva R.Zh., Kozhakhmetova Z.A., Dzhanabekova Gulmira Kumiskalievna, & Zhylkyshibayeva Meruert Malikovna. (2024). Probiotics for animals: main aspects and benefits. Scientific Research and Experimental Development, (6). Retrieved from https://ojs.publisher.agency/index.php/SRED/article/view/3461
- Myktybayeva R. Biology and Biotehnology of Microorganisms Development of starters for dairy products based on gots milk. International Conference on Microbiology ICMBB2021. 16-17 September, 2021. Tashent, Usbekistan.
- Myktybayeva R Probiotic preparation in the treatment of
bovine necrobiosis." International Journal of Agrobiotechnology and Veterinary Medicine Special Issue 2022. p. 267-274.
- Myktybayeva R. Morpho-biochemical properties of some species of non-specific urobakteries. Materials of the International Scientific and Practical Conference "Innovative Foundations of Agricultural and Bioecological Research in the Aral Sea Region," Nukus Part I, March 17, 2023, P.125-127.
6. Myktybayeva R. Influence of the antibiotic on the productivity of broiler chickens and the preservation of the herd. International Scientific and Practical Conference on the topic: "Food Security: Global and National Problems." February 22-23, 2024, P.276-278.
7. Myktybayeva R Probiotics for animals: main aspects and benefits
Veterinaty Sciences. International Scientfic Conference. publisher.agency London. C 308-312. April, 2024. № 6
Methodological Guidelines
1.Recommendation for using a probiotic prepared based on Lactobact-ARZ lactic acid bacteria. Almaty: Nur-Print Printing House, 2025. - 35 p.
2.Methodological instructions for practical classes in microbiological control of animal products. Almaty: "Aitumar" Publishing House, 2023. - 48 p.
3. Methodological instructions for laboratory classes in the subject "Microbiological Control of Animal Products." Almaty: "Aitumar" Publishing House, 2023. - 60 p.
4. Methodological guidelines for laboratory classes in Veterinary Microbiology and Immunology. Almaty: "Aitumar" Publishing House, 2023. - 57 p.
5. Methodological instructions for practical classes in the subject "Veterinary Microbiology and Immunology." Almaty: "Aitumar" Publishing House, 2023. - 48 p.
6. Methodological instructions for laboratory classes in the discipline "Veterinary Microbiology and Immunology." Almaty: "Aitumar" Publishing House, 2023. - 64 p.
7. Methodological guidelines for practical classes in the discipline "Veterinary Microbiology and Immunology"
Almaty: "Aitumar" Publishing House, 2023. - 48p.
8. Methodological instructions for laboratory classes in the discipline "Microbiological control of animal products" "Aitumar" Publishing House, 2023. - 57p.
9. Methodological guidelines for practical classes in the discipline "Microbiological control of animal products" "Aitumar" Publishing House, 2023. - 57p.
10.Methodological instructions for laboratory classes in the subject "Veterinary Microbiology and Immunology." Almaty: "Aitumar" Publishing House, 2024. - 47 p.
11.Methodological instructions for practical classes in the subject "Veterinary Microbiology and Immunology." Almaty: "Aitumar" Publishing House, 2024. - 54 p.
12.Methodological instructions for laboratory classes in "Microbiology" for 2nd-year students in "Biotechnology" SEC 12.04.2024. registration No100
13. Methodological instructions for laboratory classes in the discipline 6B05102 - "Biotechnology" for 2nd-year students of the "Microbiology" educational program 12.04.2024 No101 "Aitumar" Publishing House, 2024. - 47p.
14.Methodological instructions for laboratory classes in the subject "Microbiology" for students on the subject "Technology of Food Products" 12.04.2024 Registration No102
15. Methodological guidelines for laboratory classes in "Microbiology" for 2nd-year students studying in "Food Products Technology" SEC. 12.04.2024 Registration No103
16. Methodological instructions for laboratory classes in "Food Microbiology" 12.04.2024. Registration No98.
17. Methodological instructions for laboratory classes in "Food Microbiology" subject 12.04.2024. Registration No. 99
Bachelor’s level:
Veterinary sanitation
Food Safety
1.Certificate of professional development in the amount of 72 academic hours under the program "Optimization of lyophilic drying processes of probiotic crops in the production of functional products" at the Federal State Autonomous Educational Institution of Higher Education "National Research University" from July 07, 2025 to July 18. Registration No55.03-DPO-11/25-7981. Saint Petersburg.18.07.2025.
2.Certificate. Turkey. Ataturk University. International Congress of Veterinary Medicinal Plants. Traditional medicine and veterinary medicinal plants and traditional therapies. 30.09.2025 Erzurum city
3.Certificate.State of Turkey, Isparta city. "Ysparta University of Applied Sciences" 72 hours.16.06. 2024
4.Certificate. Requirements for dissertation work and innovative support programs in writing scientific articles. 13.04.2023
5 Certificate. Develop skills in applying the labor legislation of the Republic of Kazakhstan, negotiating labor disputes, and achieving consensus. 17. 11.2023 Registration No3500.
- Isparta University of Applied Sciences, Түркия — Ozkaya Serkan
- https://orcid.org/0000-0003-3389-0188
- Ataturk University, Түркия — Ali Dogan
Near abroad (CIS and Central Asia):
National Research University, Russia - Lyudmila Anatolyevna Nadtochiy
https://orcid.org/0000-0002-4678-8177